Damage to DNA is relatively common in our cells, and cells have evolved over the years to overcome this challenge by possessing pathways that are responsible for the repair of these damages, which could be caused by endogenous and/or exogenous carcinogenic agents. The damage done to DNA plays a major role in mutagenesis, ageing and carcinogenesis. In response to DNA damage, the cell employs mechanisms such as mismatch repair, base excision repair and nucleotide excision repair pathways in order to maintain genome stability and integrity.
I am mostly interested in how cellular responses to DNA damage, and the mechanisms that are responsible for defects in repair pathways, are activated and coordinated; and how defects in these repair pathways contribute to cancer development and progression. In addition, the process by which cell cycle checkpoints detect DNA damage and activate regulatory proteins such as p53 and other repair proteins are also of keen interest to me.
Addressing the above questions would advance my knowledge on the molecular basis of cancer development and progression and prepare me for a discipline in cancer science. Understanding the above processes will also contribute to the development of novel therapies to target proteins that are known to be implicated in cancer. This would ultimately improve the treatment and management approaches for cancer patients.
In addition to the above, I do repair laptop systems as part of my hobbies. I have on several occasions repaired my friends' systems. It has always being rewarding to see smiles on the faces of my friends after working on their systems. I can confidently handle Windows Installations, speed up a slow system, install and uninstall software and hardware, including motherboards, hard drives, video cards, etc. I am also very good at graphic design, but still learning to improve on it.
I am proficient in most of Microsoft packages such as MS Excel, Powerpoint and Word. Again, I have mastering skills in photo-editing tools such as Irfanview, Adobe Photoshop, and MS Powerpoint. I possess an advanced proficiency in working with Wordpress.