targeted therapies against CSCs

Figure 3: Targeted therapies against CSCs. Over the years, more targeted therapies against CSCs have been developed. These therapies have been classified into those that target signalling pathways that promote the CSC phenotypes (green area), targeted therapies against specific surface markers expressed by the CSCs (red area), drugs targeting ABC transporters that are known to be upregulated in CSCs (purple area) and lastly, drugs that inhibit certain growth factors and chemokines that collectively act to promote the CSC phenotypes. Figure adapted from [40].